How to Keep Your Hormones in Happy Balance
From PMS to post-partum depression to menopause, hormones can affect everything about a woman’s health. Our cognition, emotions, and overall wellness all answer—at least in part—to the current hormone balance we’re experiencing.
When your hormones are out of balance, that can cause a wide variety of symptoms and diseases… from weight gain to period pain to pregnancy problems to urinary tract infections. So as a woman, it’s especially important to do whatever you can to safely and effectively keep your hormone levels where they need to be.
That balance matters regardless of your current circumstances—like if you’re having a period, entering perimenopause, or newly pregnant, for example. And the best ways to manage hormone balance and keep yourself in optimal health may surprise you.
Your Hormones Can Make You Sick
As a woman, your health can depend on your hormones—especially estrogen. When your body has just the right amount of estrogen circulating through your body, you can feel your best. But when there’s too much or too little estrogen present, that imbalance can cause lots of symptoms and some serious health issues.
Estrogen dominance, meaning more estrogen than your body can handle, can lead to:
- Painful, heavy, or irregular periods
- Breast tenderness
- Weight gain
- Mood swings
- Increased risk for breast and uterine cancers
- Endometriosis
- PCOS (polycystic ovarian syndrome)
- Difficulty conceiving and fertility issues
- Pregnancy issues like low birth weight or premature delivery
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Low estrogen (also called estrogen deficiency) causes its own set of issues. Usually linked to menopause, this condition can also be brought on by certain cancer treatments or other issues that affect hormone production (like thyroid disease). Low estrogen can cause things like:
- Painful breasts
- Mood swings
- Brain fog
- Hot flashes and night sweats
- Infertility
- Urinary tract infections
- Osteoporosis
- Osteoarthritis
- Increased risk for cardiovascular diseases
Having too much or too little estrogen can make you feel awful and take a toll on your health and quality of life. That’s why you want your estrogen to fall into that just-right Goldilocks zone.
Get to Know Your Estrobolome
Your body knows how to manage your estrogen levels; it has a system in place dedicated to just that. Your estrobolome, a part of your gut microbiome, contains special bacteria that regulate the amount of circulating estrogen in your body.[1]
Your body bundles up any estrogen it’s not using and sends it through your digestive system to get rid of it. When that estrogen gets to the estrobolome, the bacteria there produce an enzyme called beta-glucuronidase to break down the hormone. Then it reactivates some of the estrogen and sends it back into circulation, while the rest gets excreted.[2]
When that system works correctly, you have just the amount of estrogen your body needs. But your estrobolome function depends on the health of your gut microbiome. And if that falls out of balance, the estrobolome’s estrogen management system crashes. And that can cause estrogen dominance or estrogen deficiency.[3]
Estrogen Balance Depends on Gut Microbiome Balance
Your gut microbiome, the trillions of bacteria in your gut, houses the estrobolome bacteria too. When your overall gut microbiome is in healthy balance, beneficial probiotic bacteria outnumber harmful pathogenic bacteria. Those probiotic bacteria positively influence every system in your body. That includes managing your hormones through the estrobolome.[4]
If your gut microbiome gets knocked out of balance, a condition called dysbiosis, pathogens dominate and outnumber probiotic bacteria. Gut dysbiosis destabilizes the estrobolome as well, and that disrupts the normal estrogen balancing system by changing the production of beta-glucuronidase.[5,6]
Too much beta-glucuronidase leads too much circulating estrogen and estrogen dominance.[7] Too little of the enzyme lowers circulating estrogen and causes estrogen deficiency.[3]
So the key to just-right estrogen levels depends on a healthy estrobolome, which requires a well-balanced gut microbiome. And while that’s the first step toward stabilizing your hormone levels, there’s more you can do to keep them balanced so you can feel your best.
3 Ways to Support Women’s Hormone Balance
1. Support Your Gut Health
The first step toward optimal hormone health lies in a properly balanced gut microbiome. The best way to get—and keep—your gut microbiome in that healthy state is with spore probiotics.
Unlike other probiotics you might see on the shelves, spore probiotics arrive in your gut 100% alive and ready to work. Once there, they clear out pathogens so other beneficial bacteria can flourish—exactly the support your gut needs to stay in balance. And a well-balanced gut full of a diverse population of beneficial bacteria does more than stabilize your estrobolome and hormones. It also helps to:
- Promote a healthy pregnancy[8]
- Keep periods more comfortable[9]
- Clear brain fog[10]
- Support a balanced mood[11]
- Promotes healthy weight maintenance[12]
- Eases the path through menopause[13]
2. Get Enough K2
Most people don’t get enough of this crucial vitamin[14], and it’s even more important for women. Vitamin K2 plays a key role in estrogen management and metabolism.[15] It also mitigates some of the impact of low estrogen by promoting bone density and maintaining strong, flexible blood vessels for a healthy cardiovascular system.
You’ll want to take supplements containing vitamin K2-7, the most absorbable, bioavailable form of this essential nutrient to get the most out of it.[16]
3. Nurture Your UT Health
Finally, your hormones play a huge part in urinary tract health—and you know how frustrating it can be to deal with that. You can proactively support your urinary tract even during hormone ups and downs with safe, effective, protective plant compounds.
- Cranberries, for example, contain natural compounds called PACs that can keep bacteria from sticking to the urinary tract, making it easier for your body to flush them out.[17]
- Hibiscus helps protect the urinary tract and keep it more acidic.[18]
- And black cumin seed contains a compound called TQ (thymoquinone) that helps address potential urinary tract disruptors before they can cause problems.[19]
Taking these steps can help you keep your hormones in balance so you can feel comfortable and healthy during every phase of your life.
Just Thrive Gut Health Products
Support Your Hormone, Gut, and Total Health with Just Thrive
Ladies, the key to feeling steady, comfortable, and healthy depends on your hormones. Keeping those hormones in balance can make your life easier no matter what stage of life you’re in.
You can smooth out those ups and downs by taking proactive steps to get better control over your body’s natural hormone management system: balancing your gut microbiome, shoring up your vitamin K2 supplies, and safe-guarding your urinary health.
Just Thrive Probiotic & Antioxidant promotes a wide variety of native probiotic bacteria that can grow, flourish, and deliver plentiful health benefits. It contains 4 clinically studied spore probiotics:
- Bacillus indicus HU36™
- Bacillus subtilis HU58™
- Bacillus coagulans (SC-208)
- Bacillus clausii (SC-109)
This proven quartet of spore probiotics helps keep your gut microbiome in optimal balance to support a healthy estrobolome and overall wellness.
Just Thrive Vitamin K2-7 contains all-natural pharmaceutical-grade vitamin K2-7 (the most bioavailable form of vitamin K2) and provides the optimal dose of 320 mcg daily. Plus, it includes the necessary cofactors magnesium, zinc, and vitamin K1 that help fully unlock all of K2’s wellness potential.
UT123 offers a proactive approach for urinary tract support, keeping it comfortable and healthy, with a fast-acting natural formula that contains
- 500 mg Pacran® whole cranberry extract
- 200 mg Ellirose™ hibiscus extract
- 100 mg Nigellin® black cumin seed extract
>> Enjoy total hormone health every day with support from Just Thrive Probiotic, Vitamin K2-7, and UT123.
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Sources
- Kumari N, et al. From Gut to Hormones: Unraveling the Role of Gut Microbiota in (Phyto)Estrogen Modulation in Health and Disease. Mol Nutr Food Res. 2024 Mar;68(6):e2300688.
- Ervin SM, Li H, Lim L, Roberts LR, Liang X, Mani S, Redinbo MR. Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens. J Biol Chem. 2019 Dec 6;294(49):18586-18599.
- Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas. 2017 Sep;103:45-53. doi: 10.1016/j.maturitas.2017.06.025. Epub 2017 Jun 23. PMID: 28778332.
- Siddiqui R, Makhlouf Z, Alharbi AM, Alfahemi H, Khan NA. The Gut Microbiome and Female Health. Biology (Basel). 2022 Nov 21;11(11):1683.
- Hu S, Ding Q, Zhang W, Kang M, Ma J, Zhao L. Gut microbial beta-glucuronidase: a vital regulator in female estrogen metabolism. Gut Microbes. 2023 Jan-Dec;15(1):2236749. doi: 10.1080/19490976.2023.2236749.
- Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas. 2017 Sep;103:45-53.
- Sui Y, Wu J, Chen J. The Role of Gut Microbial β-Glucuronidase in Estrogen Reactivation and Breast Cancer. Front Cell Dev Biol. 2021 Aug 12;9:631552. doi: 10.3389/fcell.2021.631552. PMID: 34458248; PMCID: PMC8388929.
- Edwards SM, Cunningham SA, Dunlop AL, Corwin EJ. The Maternal Gut Microbiome During Pregnancy. MCN Am J Matern Child Nurs. 2017 Nov/Dec;42(6):310-317. doi: 10.1097/NMC.0000000000000372. PMID: 28787280; PMCID: PMC5648614.
- Yao Y, Hu H, Chen L, Zheng H. Association between gut microbiota and menstrual disorders: a two-sample Mendelian randomization study. Front Microbiol. 2024 Mar 7;15:1321268. doi: 10.3389/fmicb.2024.1321268. PMID: 38516009; PMCID: PMC10954809.
- Liang X, et al. Gut microbiome, cognitive function and brain structure: a multi-omics integration analysis. Transl Neurodegener. 2022 Nov 14;11(1):49. doi: 10.1186/s40035-022-00323-z. PMID: 36376937; PMCID: PMC9661756.
- Martin SE, Kraft CS, Ziegler TR, Millson EC, Rishishwar L, Martin GS. The Role of Diet on the Gut Microbiome, Mood and Happiness. medRxiv [Preprint]. 2023 Mar 21:2023.03.18.23287442.
- Carmody, R.N., Bisanz, J.E. Roles of the gut microbiome in weight management. Nat Rev Microbiol 21, 535–550 (2023).
- Peters BA, Santoro N, Kaplan RC, Qi Q. Spotlight on the Gut Microbiome in Menopause: Current Insights. Int J Womens Health. 2022 Aug 10;14:1059-1072. doi: 10.2147/IJWH.S340491. PMID: 35983178; PMCID: PMC9379122.
- Bruno EJ (2016) The Prevalence of Vitamin K Deficiency/Insufficiency, and Recommendations for Increased Intake. J Hum Nutr Food Sci 4(1): 1077. Bruno EJ (2016) The Prevalence of Vitamin K Deficiency/Insufficiency, and Recommendations for Increased Intake. J Hum Nutr Food Sci 4(1): 1077.
- Otsuka M, et al. Vitamin K2 binds 17beta-hydroxysteroid dehydrogenase 4 and modulates estrogen metabolism. Life Sci. 2005 Apr 8;76(21):2473-82. doi: 10.1016/j.lfs.2004.12.020. PMID: 15763078.
- Vik H. Highlighting The Substantial Body Of Evidence Confirming The Importance Of Vitamin K2 As A Cardio-Support Nutrient, And How The Right K2 Makes All The Difference. Integr Med (Encinitas). 2019 Dec;18(6):24-28. PMID: 32549853; PMCID: PMC7238900.
- Kaspar KL, Howell AB, Khoo C. A randomized, double-blind, placebo-controlled trial to assess the bacterial anti-adhesion effects of cranberry extract beverages. Food Funct. 2015 Apr;6(4):1212-7.
- Chou ST, Lo HY, Li CC, Cheng LC, Chou PC, Lee YC, Ho TY, Hsiang CY. Exploring the effect and mechanism of Hibiscus sabdariffa on urinary tract infection and experimental renal inflammation. J Ethnopharmacol. 2016 Dec 24;194:617-625.
- Utami, AT. Nigella sativa Linn. and Lower Urinary Tract Infection Treatment. J Surg Pathol Diagn 2018, 1:1
