This blog has been update for quality and relevancy on September 18, 2025.
You wake up in a fog that doesn’t clear even after your caffeine fix. It’s hard to think, focus, and make decisions. You suddenly have trouble remembering things you absolutely know.
Your brain feels tired, overloaded, and just slower than it used to be. And you start wondering if you’ll ever feel clear again.
Welcome to the wonderful world of brain fog.
While there are a lot of misconceptions about what brain fog actually is, here’s the truth: It’s not just stress… and it’s not a “normal” sign of aging.
And, if you’re like the majority of Americans, your brain fog likely comes from just one unexpected source.
Here’s why that’s great news: By making one simple shift, you can address the root of the fog and lift the switch on your maximum brain power.
LPS Toxins, Leaky Gut, and How They Impact Your Body (and Brain)
Your large intestine—your gut—is lined with a protective barrier.[1] It uses selective permeability to allow only healthy substances, like nutrients and antioxidants, into your bloodstream while keeping bacteria, toxins, and other unhealthy particles out.
When everything is working smoothly, your gut barrier acts as a shield that keeps your whole body safe. Unfortunately, your gut barrier is highly vulnerable to threats, which include things like antibiotics and pesticide residue on foods.
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But its biggest threat comes from LPS toxins.
LPS toxins (lipopolysaccharides) are produced by harmful bacteria in your gut microbiome. And when those pathogens outnumber beneficial bacteria in your gut, your body can’t always handle the LPS toxin overload.
LPS toxins constantly attack your gut barrier until it’s weakened enough for harmful particles to sneak through. That’s a leaky gut… and it’s even more dangerous than it sounds.
With a leaky gut, pathogens and toxins escape into the bloodstream and cause problems everywhere in your body.[2]
And that includes your brain.
How Leaky Gut Causes Brain Fog
It seems like a bold claim that a leaky gut can make it easy to forget appointments… make it hard to make decisions… and make it seem near impossible to focus.
But the toxins and pathogens that make their way through the gut barrier can end up reaching your brain. So when your gut barrier isn’t functioning the way it’s supposed to, your brain power can suffer.[3]
Once harmful particles escape into your bloodstream, they can travel throughout your body and make their way to your brain… And when they get to your brain, the toxins and pathogens can harm your brain cells and brain function…which can result in brain fog.
Research shows that:
- Leaky gut and circulating LPS toxins cause brain cells to stop working properly[4]
- Patients with Alzheimer’s disease had 300% more circulating LPS toxins than healthy people[5]
- Leaky gut leads to “leaky brain,” which alters brain chemistry and causes cognitive and emotional dysfunction[6]
- Healthy adults with leaky gut and elevated LPS toxins can begin to experience cognitive decline[7]
- People with dementia have increased biomarkers for leaky gut[8]
So if you want to feel sharp, clear, and in control of your brain, you need to stop the leaks in your gut…
And one of the best ways to do that is by supporting the system that’s built to drive the health of your gut barrier.
Your Immune System Can Keep Your Brain and Gut Barrier Healthy (But It Needs Your Help)
Yes, your immune system protects your total body health, but did you know? It also acts as the master protector of your brain health.
To do its job of keeping your safe, your immune system deploys specialized defenders that ring the alarm at the first sign of a threat. Known as immunoglobulins, these frontline soldiers work 24/7 to protect you from infectious bugs and toxins. (Especially Immunoglobulin G (IgG) which makes up almost 80% of your total immune fighting force.) And their job includes keeping your gut barrier strong and safe. That part of the job is so important, in fact, that around 70-80% of your immune system is in your gut.
Unfortunately, a constant barrage of LPS toxins and pathogenic bacteria from leaky gut can overwhelm your immunoglobulins. Those unwanted villains can affect anything from joint comfort to clear thinking. And when they make their way to your brain, that’s when brain fog sets in.
That’s why, for the health of your gut barrier, brain and body, giving your immune system “IgG backup” can make all the difference.[9] ...And science has shown that one of the best ways to support your gut barrier defense team is to arm them with dedicated serum-derived bovine IgG supplements.[10]
Specific serum-derived bovine IgG is clinically proven[11] to add an extra layer of support for your gut barrier[12], can help avoid new leaks, and can even support your body’s natural ability to address existing leaks. These immunoglobulins also neutralize and bind LPS toxins and other compounds[13] so they can be safely eliminated from your body.
Just Thrive Immune Health Products
Support a Healthy Gut Barrier and a Clear, Sharp Mind with Ultimate IgG
Ultimate IgG helps maintain a healthy gut barrier with support from serum-derived bovine immunoglobulins. A strong gut barrier helps keep your whole body healthy… including your brain. So if you love being a quick thinker, having strong recall, and solving puzzles and problems without breaking a sweat, love your brain by supporting your gut barrier with Ultimate IgG. Plus, by reinforcing your own supply of immunoglobulins, Ultimate IgG also supports healthy immune system function.
Ultimate IgG is the most highly-concentrated IgG formula on the market (contains more antibodies than any other comparable product). In this powerful immune and detox supplement you get:
- IgG - the most prevalent type of antibody, accounting for about 80% of your immune power
- IgA - provides surveillance of the gut lining, the respiratory system, and other surface barriers
-
IgM - races to engage the threat and keeps it in check until your IgG joins the fight
>> Support your gut barrier, brain, and immunity with Ultimate IgG.
But if you’re feeling unsure about trying Ultimate IgG, we can help.
EVERY Just Thrive purchase is covered by our Bottom of the Bottle, 100% money back guarantee.
So you can try Ultimate IgG to see if it works for you… and we’re confident it will.
But if for any reason you don’t feel a difference, simply ask for a full product refund at any time. Even if it’s been 3 months or 3 years. Even if the bottle is empty!
Sources
- Assimakopoulos SF, Triantos C, Maroulis I, Gogos C. The Role of the Gut Barrier Function in Health and Disease. Gastroenterology Res. 2018;11(4):261-263. doi:10.14740/gr1053w
- Camilleri M. Leaky gut: mechanisms, measurement and clinical implications in humans. Gut. 2019;68(8):1516-1526. doi:10.1136/gutjnl-2019-318427
- Rogers GB, Keating DJ, Young RL, Wong ML, Licinio J, Wesselingh S. From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways. Mol Psychiatry. 2016;21(6):738-748. doi:10.1038/mp.2016.50
- Brown GC. The endotoxin hypothesis of neurodegeneration. J Neuroinflammation. 2019;16(1):180. doi:10.1186/s12974-019-1564-7
- Zhan X, Stamova B, Sharp FR. Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer's Disease Brain: A Review. Front Aging Neurosci. 2018;10:42. Published 2018 Feb 22. doi:10.3389/fnagi.2018.00042
- Obrenovich MEM. Leaky Gut, Leaky Brain?. Microorganisms. 2018;6(4):107. Published 2018 Oct 18. doi:10.3390/microorganisms6040107
- Rundek T, Roy S, Hornig M, et al. Gut permeability and cognitive decline: A pilot investigation in the Northern Manhattan Study. Brain Behav Immun Health. 2021;12:100214. doi:10.1016/j.bbih.2021.100214
- Stadlbauer V, Engertsberger L, Komarova I, et al. Dysbiosis, gut barrier dysfunction and inflammation in dementia: a pilot study. BMC Geriatr. 2020;20:248. doi:10.1186/s12877-020-01644-2
- Valentin N, Camilleri M, Carlson P, et al. Potential mechanisms of effects of serum-derived bovine immunoglobulin/protein isolate therapy in patients with diarrhea-predominant irritable bowel syndrome. Physiol Rep. 2017;5(5):e13170. doi:10.14814/phy2.13170
- Ulfman LH, Leusen JHW, Savelkoul HFJ, Warner JO, van Neerven RJJ. Effects of bovine immunoglobulins on immune function, allergy, and infection. Front Nutr. 2018;5:52. doi:10.3389/fnut.2018.00052
- Soriano RA, Ramos-Soriano AG. Clinical and Pathologic Remission of Pediatric Ulcerative Colitis with Serum-Derived Bovine Immunoglobulin Added to the Standard Treatment Regimen. Case Rep Gastroenterol. 2017;11(2):335-343. Published 2017 May 19. doi:10.1159/000475923
- Utay NS, Somasunderam A, Hinkle JE, et al. Serum Bovine Immunoglobulins Improve Inflammation and Gut Barrier Function in Persons with HIV and Enteropathy on Suppressive ART. Pathog Immun. 2019;4(1):124-146. Published 2019 May 3. doi:10.20411/pai.v4i1.276
- Utay NS, Asmuth DM, Gharakhanian S, Contreras M, Warner CD, Detzel CJ. Potential use of serum-derived bovine immunoglobulin/protein isolate for the management of COVID-19. Drug Dev Res. 2021;82(7):927-932. doi:10.1002/ddr.21841
