Have you been feeling off? Tired all the time no matter how much you sleep. Your brain feels like it’s in slow mode. Mood all over the place. Achy joints.
You’ve been dealing with issues that have no obvious source. Your doctor can’t find anything wrong, maybe even suggests it’s all in your head.
But it might actually be in your gut.
You could have silent celiac disease. And if you don’t take steps to manage it, things could get a lot worse.
Celiac Doesn’t Always Present in an Obvious Way
The clearest signs of celiac disease involve digestive problems like diarrhea, constipation, gas, and bloating whenever you eat gluten. But not everyone gets those either.[1]
Some people have hidden issues, like fatigue or joint pain, that they’d never connect to eating gluten. Those cases are called silent or asymptomatic celiac.[2] And they’re even more common. According to the Celiac Disease Foundation, an estimated 80% of people with celiac remain undiagnosed.
And even though the symptoms are hidden, that doesn’t mean the disease isn’t damaging your body.
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Gluten Causes Gut Damage Even Without Gut Problems
Whether or not you notice it, celiac disease harms your gut.
When you have celiac disease, any gluten you eat triggers an immune inflammatory response. Your body attacks your small intestine, harming the villi (small thread-like projections) that line it.[3] That damage to the villi can prevent you from absorbing nutrients from your food.
Gluten is a naturally destructive protein.[4] It has many more negative effects on the body on top of triggering inflammation. Research shows that gluten can:[5]
- unbalance the gut microbiome
- cause leaky gut
- increase oxidative stress
- interfere with normal cell function
All of that adds up, and the direct harm to the small intestine is cumulative. While gluten remains in your diet, the damage just keeps building up. Even if you remove gluten from your diet, the existing damage can take years to repair.[6]
Gluten Has Hidden Effects On Your Body
Because of all the damage it does, especially to your immune system, gluten can cause a wide variety of health problems that seem completely unrelated. Many of these are due to improper immune system responses, others from gut microbiome imbalances and leaky gut, and others due to malabsorption and malnutrition.
Research shows that nearly 90% of people with celiac disease, whether they know they have it or not, are severely deficient in several nutrients including B vitamins, vitamins A and D, zinc, iron, and calcium.[7]
Some of those hidden effects of gluten include:
- anemia[8]
- extreme fatigue[9]
- neuropathy (nerve damage)[10]
- brain fog[11]
- dental problems (including weakened or discolored enamel)[12]
- infertility[13]
- depression and anxiety[14]
- elevated liver enzymes[15]
- painful skin rashes[16]
- muscle and joint pain[17,18]
- osteoporosis[19]
If you’re dealing with any of these issues, you may have celiac disease. Even if you don’t think you have celiac, it makes sense to get tested. And, more important, go gluten-free for at least one month.
If you start to feel better… gluten is the problem.
How to Handle Accidental Gluten
Going gluten-free is the only way to manage celiac disease long-term. It stops the constant damage gluten causes, and it gives your body a chance to repair your intestines, and that can take years to happen.
But eating any gluten at all can reactivate the immune system attacks, create new damage, and thwart your progress.
Unfortunately, many foods with gluten-free labels do contain gluten. Studies show that up to 40% of gluten-free foods sampled had gluten in them.[20] Plus, many foods you wouldn’t expect to contain gluten—like pickles, licorice, and salad dressing—actually do.
Then there’s cross-contamination. If any flour or other gluten-containing foods are in a kitchen, either at your home or in a restaurant, you can be exposed to that gluten accidentally.
All of that makes it very hard to avoid gluten completely, even when you’re doing your best to stick to a gluten-free diet. But there is a way to safeguard yourself against accidental gluten ingestion.
The human body can’t break down gluten fully. It needs assistance from a special enzyme called Tolerase G that converts unmanageable gluten proteins into much smaller pieces that your body can handle more easily.
And if you’re going through the trouble of eating gluten-free, you’ll want to give your gut as much support as you can. You can support that process with special probiotics that produce compounds called short chain fatty acids (SCFAs), which help maintain gut barrier integrity and balanced immune responses.[21] Each of these specialized probiotics bring added benefits to promote a healthy gut:
- Saccharomyces boulardii is a clinically studied probiotic yeast known to help dissolve gluten proteins and support complete nutrient absorption and gastrointestinal (GI) comfort.[22,23].
- Bacillus coagulans is a spore probiotic that quickly comforts and nurtures a gut irritated by gluten[24] and can help your gut barrier prevent toxins from leaking into your bloodstream.
- Bacillus subtilis, another spore probiotic, offers balanced immune system support and promotes SCFA production to nourish the gut barrier.[25,26]
Bottom line: In combination with going gluten-free, these enzymes and probiotics help to nourish your intestinal lining and break down gluten you are accidentally exposed to before it causes trouble.
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Calm Your Gluten Fears with Gluten Away
Avoiding gluten is a critical step for protecting your health. And you can safeguard yourself against hidden gluten and cross contamination by giving your body the defenses it needs against accidental gluten exposure.
Gluten Away contains:
- Gluten-crushing enzyme, Tolerase G
- Gut-nourishing probiotics Bacillus subtilis HU58, Bacillus coagulans, and Saccharomyces boulardii
- Betaine HCl for healthy stomach acid levels
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Sources
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- Çaltepe G. The hidden danger: Silent celiac disease. Turk J Gastroenterol. 2018;29(5):530-531. doi:10.5152/tjg.2018.280818
- Schiepatti A, et al. Persistent villous atrophy predicts development of complications and mortality in adult patients with coeliac disease: a multicentre longitudinal cohort study and development of a score to identify high-risk patients. Gut. 2023 Nov;72(11):2095-2102.
- Kõiv V, Tenson T. Gluten-degrading bacteria: availability and applications. Appl Microbiol Biotechnol. 2021 Apr;105(8):3045-3059.
- Lerner A, Shoenfeld Y, Matthias T. Adverse effects of gluten ingestion and advantages of gluten withdrawal in nonceliac autoimmune disease. Nutr Rev. 2017 Dec 1;75(12):1046-1058.
- Welstead L. The Gluten-Free Diet in the 3rd Millennium: Rules, Risks and Opportunities. Diseases. 2015 Jul 13;3(3):136-149
- Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA. Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients. Nutrients. 2013 Sep 30;5(10):3975-92.
- Valvano M, Giansante C, Vinci A, Maurici M, Fabiani S, Stefanelli G, Cesaro N, Viscido A, Caloisi C, Latella G. Persistence of anemia in patients with Celiac disease despite a gluten free diet: a retrospective study. BMC Gastroenterol. 2025 Mar 3;25(1):128.
- Skjellerudsveen BM, Omdal R, Grimstad T. Fatigue in celiac disease: A review of the literature. JGH Open. 2019 Jan 8;3(3):242-248.
- Mearns ES, Taylor A, Thomas Craig KJ, Puglielli S, Cichewicz AB, Leffler DA, Sanders DS, Lebwohl B, Hadjivassiliou M. Neurological Manifestations of Neuropathy and Ataxia in Celiac Disease: A Systematic Review. Nutrients. 2019; 11(2):380.
- Croall ID, Hoggard N, Aziz I, Hadjivassiliou M, Sanders DS. Brain fog and non-coeliac gluten sensitivity: Proof of concept brain MRI pilot study. PLoS One. 2020 Aug 28;15(8):e0238283.
- Inchingolo AD, et al. Celiac Disease-Related Enamel Defects: A Systematic Review. J Clin Med. 2024 Feb 28;13(5):1382.
- Freeman HJ. Reproductive changes associated with celiac disease. World J Gastroenterol. 2010 Dec 14;16(46):5810-4.
- Clappison E, Hadjivassiliou M, Zis P. Psychiatric Manifestations of Coeliac Disease, a Systematic Review and Meta-Analysis. Nutrients. 2020 Jan 4;12(1):142.
- Villavicencio Kim J, Wu GY. Celiac Disease and Elevated Liver Enzymes: A Review. J Clin Transl Hepatol. 2021 Feb 28;9(1):116-124. doi: 10.14218/JCTH.2020.00089. Epub 2020 Dec 7. PMID: 33604262; PMCID: PMC7868701.
- Pasternack C, Hervonen K, Mansikka E, Reunala T, Collin P, Kaukinen K, Salmi T. Persistent Skin Symptoms after Diagnosis and on a Long-term Gluten-free Diet in Dermatitis Herpetiformis. Acta Derm Venereol. 2021 Sep 22;101(9):adv00555.
- Jericho H, Sansotta N, Guandalini S. Extraintestinal Manifestations of Celiac Disease: Effectiveness of the Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):75-79.
- Priyadarshini S, Asghar A, Shabih S, Kasireddy V. Celiac Disease Masquerading as Arthralgia. Cureus. 2022 Jun 28;14(6):e26387.
- Bommu VJL, Mirza L. Osteoporosis Can Be the Sole Presentation in Celiac Disease. Cureus. 2021 Dec 22;13(12):e20602.
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- Parada Venegas D, De la Fuente MK, Landskron G, González MJ, Quera R, Dijkstra G, Harmsen HJM, Faber KN, Hermoso MA. Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases. Front Immunol. 2019 Mar 11;10:277.
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- Shinde T, Perera AP, Vemuri R, Gondalia SV, Karpe AV, Beale DJ, Shastri S, Southam B, Eri R, Stanley R. Synbiotic Supplementation Containing Whole Plant Sugar Cane Fibre and Probiotic Spores Potentiates Protective Synergistic Effects in Mouse Model of IBD. Nutrients. 2019 Apr 11;11(4):818.
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